noise annoyance; human experiment; aircraft noise; epidemiology; sleep; transportation noise; cardiovascular diseases; railway noise; noise modeling; road traffic noise; metabolic syndrome; acoustics
Cerletti Paco, Eze Ikenna C., Schaffner Emmanuel, Foraster Maria, Viennau Danielle, Cajochen Christian, Wunderli Jean-Marc, Röösli Martin, Stolz Daiana, Pons Marco, Imboden Medea, Probst-Hensch Nicole (2020), The independent association of source-specific transportation noise exposure, noise annoyance and noise sensitivity with health-related quality of life, in Environment International
, 143, 105960-105960.
Rudzik Franziska, Thiesse Laurie, Pieren Reto, Héritier Harris, Eze Ikenna C, Foraster Maria, Vienneau Danielle, Brink Mark, Wunderli Jean Marc, Probst-Hensch Nicole, Röösli Martin, Fulda Stephany, Cajochen Christian (2020), Ultradian modulation of cortical arousals during sleep: effects of age and exposure to nighttime transportation noise, in Sleep
, 43(7), zsz324.
Eze Ikenna C., Jeong Ayoung, Schaffner Emmanuel, Rezwan Faisal I., Ghantous Akram, Foraster Maria, Vienneau Danielle, Kronenberg Florian, Herceg Zdenko, Vineis Paolo, Brink Mark, Wunderli Jean-Marc, Schindler Christian, Cajochen Christian, Röösli Martin, Holloway John W., Imboden Medea, Probst-Hensch Nicole (2020), Genome-Wide DNA Methylation in Peripheral Blood and Long-Term Exposure to Source-Specific Transportation Noise and Air Pollution: The SAPALDIA Study, in Environmental Health Perspectives
, 128(6), 067003-067003.
Thiesse Laurie, Rudzik Franziska, Kraemer Jan F., Spiegel Karine, Leproult Rachel, Wessel Niels, Pieren Reto, Héritier Harris, Eze Ikenna C., Foraster Maria, Garbazza Corrado, Vienneau Danielle, Brink Mark, Wunderli Jean Marc, Probst-Hensch Nicole, Röösli Martin, Cajochen Christian (2020), Transportation noise impairs cardiovascular function without altering sleep: The importance of autonomic arousals, in Environmental Research
, 182, 109086-109086.
Brink, Schäffer, Vienneau, Pieren, Foraster, Eze, Rudzik, Thiesse, Cajochen, Probst-Hensch, Röösli, Wunderli (2019), Self-Reported Sleep Disturbance from Road, Rail and Aircraft Noise: Exposure-Response Relationships and Effect Modifiers in the SiRENE Study, in International Journal of Environmental Research and Public Health
, 16(21), 4186-4186.
Héritier Harris, Vienneau Danielle, Foraster Maria, Eze Ikenna C, Schaffner Emmanuel, de Hoogh Kees, Thiesse Laurie, Rudzik Franziska, Habermacher Manuel, Köpfli Micha, Pieren Reto, Brink Mark, Cajochen Christian, Wunderli Jean Marc, Probst-Hensch Nicole, Röösli Martin (2019), A systematic analysis of mutual effects of transportation noise and air pollution exposure on myocardial infarction mortality: a nationwide cohort study in Switzerland, in European Heart Journal
, 40(7), 598-603.
Sieber Chloé, Ragettli Martina S., Brink Mark, Olaniyan Toyib, Baatjies Roslyn, Saucy Apolline, Vienneau Danielle, Probst-Hensch Nicole, Dalvie Mohamed Aqiel, Röösli Martin (2018), Comparison of sensitivity and annoyance to road traffic and community noise between a South African and a Swiss population sample, in Environmental Pollution
, 241, 1056-1062.
Cantuaria Manuella Lech, Usemann Jakob, Proietti Elena, Blanes-Vidal Victoria, Dick Bernhard, Flück Christa E., Rüedi Simone, Héritier Harris, Wunderli Jean-Marc, Latzin Philipp, Frey Urs, Röösli Martin, Vienneau Danielle (2018), Glucocorticoid metabolites in newborns: A marker for traffic noise related stress?, in Environment International
, 117, 319-326.
Rudzik Franziska, Thiesse Laurie, Pieren Reto, Wunderli Jean Marc, Brink Mark, Foraster Maria, Héritier Harris, Eze Ikenna C, Garbazza Corrado, Vienneau Danielle, Probst-Hensch Nicole, Röösli Martin, Cajochen Christian (2018), Sleep spindle characteristics and arousability from nighttime transportation noise exposure in healthy young and older individuals, in Sleep
Locher Barbara, Piquerez André, Habermacher Manuel, Ragettli Martina, Röösli Martin, Brink Mark, Cajochen Christian, Vienneau Danielle, Foraster Maria, Müller Uwe, Wunderli Jean Marc (2018), Differences between Outdoor and Indoor Sound Levels for Open, Tilted, and Closed Windows., in International journal of environmental research and public health
, 15(1), 149.
Héritier Harris, Danielle Vienneau, Maria Foraster, Ikenna C. Eze, Emanuel Schaffner, Laurie Thiesse, Fanziska Rudzik, Manuel Habermacher, Micha Kopfli, Reto Pieren, Arno Schmidt-Trucksäss, Mark Brink, Christian Cajochen, Jean Marc Wunderli, Nicole Probst-Hensch, Martin Röösli (2018), Diurnal variability of transportation noise exposure and cardiovascular mortality: a nationwide cohort study from Switzerland, in International Journal of Hygiene and Environmental Health
, 221, 556-563.
Eze Ikenna C, Imboden Medea, Foraster Maria, Schaffner Emmanuel, Kumar Ashish, Vienneau Danielle, Héritier Harris, Rudzik Franziska, Thiesse Laurie, Pieren Reto, von Eckardstein Arnold, Schindler Christian, Brink Mark, Wunderli Jean-Marc, Cajochen Christian, Röösli Martin, Probst-Hensch Nicole (2017), Exposure to Night-Time Traffic Noise, Melatonin-Regulating Gene Variants and Change in Glycemia in Adults., in International journal of environmental research and public health
, 14(12), 1492.
Vienneau Danielle, de Hoogh Kees, Faeh David, Kaufmann Marco, Wunderli Jean Marc, Röösli Martin, Röösli Martin (2017), More than clean air and tranquillity: Residential green is independently associated with decreasing mortality., in Environment international
, 108, 176-184.
Sieber Chloé, Ragettli Martina S, Brink Mark, Toyib Olaniyan, Baatjies Roslyn, Saucy Apolline, Probst-Hensch Nicole, Dalvie Mohamed Aqiel, Röösli Martin (2017), Land Use Regression Modeling of Outdoor Noise Exposure in Informal Settlements in Western Cape, South Africa., in International journal of environmental research and public health
, 14(10), 1262.
Foraster Maria, Eze Ikenna C, Schaffner Emmanuel, Vienneau Danielle, Héritier Harris, Endes Simon, Rudzik Franziska, Thiesse Laurie, Pieren Reto, Schindler Christian, Schmidt-Trucksäss Arno, Brink Mark, Cajochen Christian, Marc Wunderli Jean, Röösli Martin, Probst-Hensch Nicole (2017), Exposure to Road, Railway, and Aircraft Noise and Arterial Stiffness in the SAPALDIA Study: Annual Average Noise Levels and Temporal Noise Characteristics., in Environmental health perspectives
, 125(9), 097004-097004.
Eze I.C., Foraster M., Schaffner E., Vienneau D., Héritier H., Rudzik F., Thiesse L., Pieren R, Imboden M., von Eckardstein A., Schindler C., Brink M., Cajochen C., Wunderli J.M., Röösli M., Probst-Hensch N. (2017), Long-term exposure to transportation noise and air pollution in relation to incident diabetes in the SAPALDIA study, in International Journal of Epidemiology
, 46(4), 1115-1125.
Héritier H., Vienneau D., Foraster M., Eze I.C., Schaffner E., Thiesse L., Rudzik F., Habermacher M., Köpfli M., Pieren R., Brink M., Cajochen C., Wunderli J.M., Probst-Hensch N., Röösli M. for the SNC study group (2017), Transportation noise exposure and cardiovascular mortality: a nationwide cohort study from Switzerland., in European Journal of Epidemiology
, 32, 307-315.
Felix Schlatter, André Piquerez, Manuel Habermacher, Martina S. Ragettli, Martin Röösli, Mark Brink, Christian Cajochen, Nicole Probst-Hensch, Maria Foraster, Jean Marc Wunderli (2017), Validation of large scale noise exposure modeling by long-term measurements, in Noise Mapping
, 4, 75-86.
Brink Mark, Schreckenberg Dirk, Vienneau Danielle, Cajochen Christian, Wunderli Jean-Marc, Probst-Hensch Nicole, Röösli Martin (2016), Effects of Scale, Question Location, Order of Response Alternatives, and Season on Self-Reported Noise Annoyance Using ICBEN Scales: A Field Experiment., in International journal of environmental research and public health
, 13(11), 1-19.
Wunderli Jean Marc, Pieren Reto, Habermacher Manuel, Vienneau Danielle, Cajochen Christian, Probst-Hensch Nicole, Röösli Martin, Brink Mark (2016), Intermittency ratio: A metric reflecting short-term temporal variations of transportation noise exposure, in Journal of Exposure Science and Environmental Epidemiology
, 26, 575-585.
Foraster Maria, Eze Ikenna C, Vienneau Danielle, Brink Mark, Cajochen Christian, Caviezel Seraina, Héritier Harris, Schaffner Emmanuel, Schindler Christian, Wanner Miriam, Wunderli Jean-Marc, Röösli Martin, Probst-Hensch Nicole (2016), Long-term transportation noise annoyance is associated with subsequent lower levels of physical activity., in Environment international
, 91, 341-9.
Vienneau Danielle, Schindler Christian, Perez Laura, Probst-Hensch Nicole, Röösli Martin (2015), The relationship between transportation noise exposure and ischemic heart disease: A meta-analysis, in Environmental Research
, 138, 372-380.
Karipidis Ioannis, Vienneau Danielle, Habermacher Manuel, Köpfli Mischa, Brink Mark, Probst-Hensch Nicole, Röösli Martin, Wunderlin Jean-Marc (2014), Reconstruction of historical noise exposure data for environmental epidemiology in Switzerland within the SiRENE project, in Noise Mapping
, 1, 3-14.
Karipidis Ioannis, Köpfli Mischa, Vienneau Danielle, Brink Mark, Cajochen Christian, Probst-Hensch Nicole, Röösli Martin, Schäffer Beat, Wunderli Jean-Marc (2014), SiRENE - an interdisciplinary study on the health effects of transportation noise exposure: noise calculation solutions on the example of air traffic
, Forum Acusticum, Krakau.
Héritier Harris, Vienneau Danielle, Frei Patricia, Eze Ikenna, Brink Mark, Probst-Hensch Nicole, Röösli Martin (2014), The association between road traffic noise exposure, annoyance and health-related quality of life (HRQOL), in International Journal of Environmental Research and Public Health
, 11, 12652-12667.
Vienneau Danielle, Perez Laura, Schindler Christian, Lieb Christoph, Sommer Heini, Probst-Hensch Nicole, Künzli Nino, Röösli Martin (2014), Years of life lost and morbidity cases attributable to transportation noise and air pollution: A comparative health risk assessment for Switzerland in 2010, in International Journal of Hygiene and Environmental Health
, 218(6), 514-521.
Background: Little is known about how acute and short-term noise effects, especially those that are observed during sleep, translate into long-term health consequences. In particular, it is unclear which acoustical characteristics of noise from different sources are most detrimental for human health and wellbeing.Aims: The overall goal of this project is to investigate the acute, short- and long-term effects of road, railway and aircraft noise exposure on annoyance and coping responses, sleep disturbances and cardiometabolic risk by mutually combining human experimental research in the laboratory with population-based epidemiological methods. The project specifically aims at identifying the noise exposure patterns that most strongly affect individuals during sleep and that may result in long-term health consequences, in particular, in cardiovascular diseases and metabolic syndrome. Besides the effect of noise exposure, the role of individual characteristics such as age and gender, noise sensitivity and genetic predispositions will be elucidated.Methods: This interdisciplinary study consists of three sub-projects. Sub-project 1 focuses on the modelling of road, railway and aircraft noise exposure and its effects on annoyance and coping responses in the Swiss population. Exposure modelling will be considerably refined to reflect not only average exposure, but additional exposure characteristics such as the degree of intermittence of noise events that we hypothesise to be a relevant predictor of detrimental effects of noise during sleep. Furthermore, realistic transportation noise exposure scenarios will be compiled in Sub-project 1 and played back in sleep laboratory experiments in Sub-project 2. In Sub-project 2 acute (e.g. awakening reactions) and short-term (e.g. cardiometabolic and cognitive effects on the subsequent day) consequences of nocturnal noise exposure scenarios will be investigated in a well controlled environment by employing a counterbalanced randomised cross-over design with 48 volunteers constantly monitored during 6 nights and 5 days. In Sub-project 3 data of two on-going large SNF-funded population-based epidemiological studies (SAPALDIA biobank and Swiss National Cohort) will be used to investigate long-term cardiometabolic risk with high statistical power and by considering relevant co-factors. The three Sub-projects are designed to closely interact in an interdisciplinary manner. Sub-project 1 will provide the noise exposure scenarios and exposure set-up for Sub-project 2 and the exposure modelling for Sub-project 3. The same cardiometabolic outcomes of Sub-project 3 available from several thousand SAPALDIA study participants will also be collected in Sub-project 2 with high time resolution under controlled experimental conditions. Significance: Mutually combining human experimental and epidemiological research to systematically address acute, short- and long-term noise effects on sleep and cardiometabolic outcomes is an asset of this study and has rarely been done in noise effect research before. Experimental research allows for evaluating the effects of well defined acoustical noise exposure scenarios in a controlled environment on carefully selected, representative individuals. The use of ongoing large-scale population-based epidemiologic studies enables cost-efficiently addressing the full range of variability in the population and in exposure circumstances that occur in our environment. This will be the first study on transportation noise effects that considers genetic variations, which will provide a better understanding of relevant biological pathways. Systematic consideration of transportation noise exposure levels as well as other noise characteristics, such as the distribution of noise events during the night, is a unique feature of this project and is highly relevant for adequate regulation of noise emissions of different transportation modes. It is estimated that Switzerland, by about 2020, will have invested a substantial >5 billion Swiss francs in noise abatement measures. Thus, beyond scientific there is a high policy interest in our research questions and the results of this project are expected to have a broad impact by revealing evidence-based measures of action in order to most effectively invest these resources.