Brelsford Alan, Dufresnes Christophe, Perrin Nicolas (2016), High-density sex-specific linkage maps of a European tree frog (Hyla arborea) identify the sex chromosome without information on offspring sex., in Heredity
, 116(2), 177-181.
Brelsford A, Dufresnes C, Perrin N (2016), Trans-species variation in Dmrt1 is associated with sex determination in four European tree-frog species., in Evolution
, 70(4), 840-847.
Dufresnes Christophe, Majtyka Tomasz, Baird Stuart, Gerchen Jörn, Borzée Amaël, Ogielska Maria, Perrin Nicolas, Stöck Mathias (2016), Empirical evidence for large X-effects in animals with undifferentiated sex chromosomes, in Scientific Reports
, 6, 21029.
Brelsford Alan, Rodrigues Nicolas, Perrin Nicolas (2016), High-density linkage maps fail to detect any genetic component to sex determination in a Rana temporaria family., in Journal of Evolutionary Biology
, 29(1), 220-225.
Dufresnes Christophe, Pellet Jérôme, Bettinelli-Riccardi Sandra, Thiébaud Jacques, Perrin Nicolas, Fumagalli Luca (2016), Massive genetic introgression in threatened northern crested newts (Triturus cristatus) by an invasive congener (T. carnifex) in Western Switzerland, in Conservation Genetics
, 17, 839-846.
Rodrigues Nicolas, Vuille Yvan, Brelsford Alan, Merilä Juha, Perrin Nicolas (2016), The genetic contribution to sex determination and number of sex chromosomes vary among populations of common frogs (Rana temporaria)., in Heredity
, 117(1), 25-32.
Dufresnes Christophe, Perrin Nicolas (2015), Effect of biogeographic history on population vulnerability in European amphibians., in Conservation Biology
, 29(4), 1235-1241.
Dufresnes Christophe, Dubey Sylvain, Ghali Karim, Canestrelli Daniele, Perrin Nicolas (2015), Introgressive hybridization of threatened European tree frogs (Hyla arborea) by introduced H. intermedia in Western Switzerland, in Conservation Genetics
, 16(6), 1507-1513.
Betto-Colliard Caroline, Sermier Roberto, Litvintchuk Spartak, Perrin Nicolas, Stöck Mathias (2015), Origin and genome evolution of polyploid green toads in Central Asia: evidence from microsatellite markers., in Heredity
, 114(3), 300-308.
Rodrigues Nicolas, Vuille Yvan, Loman Jon, Perrin Nicolas (2015), Sex-chromosome differentiation and 'sex races' in the common frog (Rana temporaria)., in Proceedings of the Royal Society B / Biological Sciences
, 282(1806), 20142726.
Dufresnes Christophe, Borzée Amaël, Horn Agnès, Stöck Mathias, Ostini Massimo, Sermier Roberto, Wassef Jérôme, Litvintchuk Spartak, Kosch Tiffany, Waldman Bruce, Jang Yikweon, Brelsford Alan, Perrin Nicolas (2015), Sex-Chromosome Homomorphy in Palearctic Tree Frogs Results from Both Turnovers and X-Y Recombination., in Molecular Biology and Evolution
, 32(9), 2328-2337.
Dufresnes Christophe, Brelsford Alan, Crnobrnja-Isailović Jelka, Tzankov Nikolay, Lymberakis Petros, Perrin Nicolas (2015), Timeframe of speciation inferred from secondary contact zones in the European tree frog radiation (Hyla arborea group)., in BMC Evolutionary Biology
, 15, 155.
Bachtrog Doris, Mank Judith, Peichel Cathy, Kirkpatrick Mark, Otto Sarah, Ashman Tia-Lynn, Hahn Mathew, Kitano Jun, Mayrose Ite, Ming Ray, Perrin Nicolas, Ross Laura, Valenzuela Nicole, Vamosi Jana (2014), Sex determination: why so many ways of doing it?, in PLoS Biology
, 12(7), e1001899.
Beukeboom Leo, Perrin Nicolas (2014), The evolution of sex determination
, Oxford University Press, Oxford.
Dufresnes Christophe, Litvinchuk Spartak, Leuenberger Julien, Gahli Karim, Zinenko Oleksandr, Stöck Mathias, Perrin Nicolas, Evolutionary melting pots: a biodiversity hotspot shaped by ring diversifications around the Black Sea in the Eastern tree frog (Hyla orientalis)., in Molecular Ecology
Non-recombining sex chromosomes are expected to accumulate deleterious mutations under the combined effects of Muller’s ratchet and Hill-Robertson effects, and for this reason to progressively degenerate. Such decay has been largely documented in birds and mammals, most of which have strongly heteromorphic sex chromosomes with degenerated W and Y, respectively. In sharp contrast, however, cold-blooded vertebrates rarely show such a differentiation, even when sex determination is purely genetic. The present project aims at investigating the evolutionary dynamics of non-degenerating sex chromosomes, using amphibians as model organisms.