collection samples; historical DNA; next-generation-sequencing; genetic diversity; range contraction; ancient DNA; ecological niche modelling; climate change; spatially explicit coalescent simulations; macrofossils
Pitteloud Camille, Arrigo Nils, Suchan Tomasz, Mastretta-Yanes Alicia, Vila Roger, Dincă Vlad, Hernández-Roldán Juan, Brockmann Ernst, Chittaro Yannick, Kleckova Irena, Fumagalli Luca, Buerki Sven, Pellissier Loïc, Alvarez Nadir (2017), Climatic niche evolution is faster in sympatric than allopatric lineages of the butterfly genus Pyrgus, in Proceedings of the Royal Society B: Biological Sciences
, 284(1852), 20170208-20170208.
Ren Guangpeng, Mateo Rubén G., Liu Jianquan, Suchan Tomasz, Alvarez Nadir, Guisan Antoine, Conti Elena, Salamin Nicolas (2017), Genetic consequences of Quaternary climatic oscillations in the Himalayas: Primula tibetica as a case study based on restriction site-associated DNA sequencing, in New Phytologist
, 213(3), 1500-1512.
Schmid Sarah, Genevest Rémi, Gobet Erika, Suchan Tomasz, Sperisen Christoph, Tinner Willy, Alvarez Nadir (2017), HyRAD-X, a versatile method combining exome capture and RAD sequencing to extract genomic information from ancient DNA, in Methods in Ecology and Evolution
Delplancke M, Yazbek M, Arrigo N, Espindola A, Joly H, Alvarez N (2016), Combining conservative and variable markers to infer the evolutionary history of Prunus subgen. Amygdalus sl under domestication., in Genetic Resources and Crop Evolution
, 63, 221.
Salgado Ana L., Suchan Tomasz, Pellissier Loïc, Rasmann Sergio, Ducrest Anne-Lyse, Alvarez Nadir (2016), Differential phenotypic and genetic expression of defence compounds in a plant–herbivore interaction along elevation, in Royal Society Open Science
, 3(9), 160226-160226.
Suchan Tomasz, Pitteloud Camille, Gerasimova Nadezhda S, Kostikova Anna, Schmid Sarah, Arrigo Nils, Pajkovic Mila, Ronikier Michał, Alvarez Nadir (2016), Hybridization Capture Using RAD Probes (hyRAD), a New Tool for Performing Genomic Analyses on Collection Specimens., in PloS one
, 11(3), 0151651-0151651.
Pellissier L, Eidesen PB, Ehrich D, Schönswetter P, Tribsch A, Westergaard K, Alvarez N, Guisan A, Zimmermann NE, Normand S, Vittoz P, Luoto M, Damgaard C, Brochmann C, Wisz MS, Alsos IG (2016), Past climate-driven range shifts and population genetic diversity in Arctic plants., in Journal of Biogeography
, 43, 461.
Suchan Tomasz, Beauverd Mélanie, Trim Naïké, Alvarez Nadir (2015), Asymmetrical nature of the Trollius - Chiastocheta interaction: insights into the evolution of nursery pollination systems, in Ecology and Evolution
, 5(21), 4766-4777.
Triponez Yann, Arrigo Nils, Espíndola Anahí, Alvarez Nadir (2015), Decoupled post-glacial history in mutualistic plant-insect interactions: insights from the yellow loosestrife ( Lysimachia vulgaris) and its associated oil-collecting bees ( Macropis europaea and M. fulvipes ), in Journal of Biogeography
, 42(4), 630-640.
Triponez Yann, Arrigo Nils, Espindola Anahi, Alvarez Nadir (2015), Decoupled post-glacial history in mutualistic plant-insect interactions: insights from the yellow loosestrife (Lysimachia vulgaris) and its associated oil-collecting bees (Macropis europaea and M-fulvipes), in JOURNAL OF BIOGEOGRAPHY
, 42(4), 630-640.
Suchan Tomasz, Alvarez Nadir (2015), Fifty years after Ehrlich and Raven, is there support for plant-insect coevolution as a major driver of species diversification?, in Entomologia Experimentalis et Applicata
, 157(1), 98-112.
Mastretta-Yanes A., Arrigo N., Alvarez N., Jorgensen T. H., Piñero D., Emerson B. C. (2015), Restriction site-associated DNA sequencing, genotyping error estimation and de novo assembly optimization for population genetic inference, in Molecular Ecology Resources
, 15(1), 28-41.
Mastretta-Yanes A, Arrigo N, Alvarez N, Jorgensen T H, Piñero D, Emerson B C (2015), Restriction site-associated DNA sequencing, genotyping error estimation and de novo assembly optimization for population genetic inference., in Molecular ecology resources
, 15(1), 28-41.
Mastretta-Yanes Alicia, Zamudio Sergio, Jorgensen Tove H, Arrigo Nils, Alvarez Nadir, Piñero Daniel, Emerson Brent C (2014), Gene duplication, population genomics, and species-level differentiation within a tropical mountain shrub., in Genome biology and evolution
, 6(10), 2611-24.
Pajkovic Mila, Lappe Sylvain, Barman Rachel, Parisod Christian, Neuenschwander Samuel, Goudet Jerome, Alvarez Nadir, Guadagnuolo Roberto, Felber François, Arrigo Nils (2014), Wheat alleles introgress into selfing wild relatives: empirical estimates from approximate Bayesian computation in Aegilops triuncialis., in Molecular ecology
, 23(20), 5089-101.
Gugerli Felix, Alvarez Nadir, Tinner Willy (2013), A deep dig-hindsight on Holocene vegetation composition from ancient environmental DNA, in Molecular Ecology
, 22(13), 3433-3436.
Suchan T Beauverd M Trim N Alvarez N, Asymmetrical nature of the Trollius-Chiastocheta interaction: insights into the evolution of nursery pollination systems., in Ecology and Evolution
Gori Kevin, Suchan Tomasz, Alvarez Nadir, Goldman Nick, Dessimoz Christophe, Clustering Genes of Common Evolutionary History., in Molecular Biology and Evolution
Suchan T Alvarez N, Fifty years after Ehrlich and Raven, is there support for plant-insect coevolution as a major driver of species diversification?, in Entomologia experimentalis et applicata
Arrigo N, de la Harpe M, Litsios G, Zozomova J, Španiel S, Marhold K, Barker M, Alvarez N, Is hybridization driving the evolution of climatic niche in Alyssum montanum, in American Journal of Botany
Kébé K, Alvarez N, Espindola A, Justy F, Olivieri I, Sembène M, The bean beetle Callosobruchus maculatus is a worldwide generalist legume seed pest, present in the tropics and subtropics. Despite its economic importance, little is known about the population struct, in Journal of Pest Science
Kenyon SG Hansson C Buerki S Alvarez N* Benrey B*, Uncovering cryptic parasitoid diversity in Horismenus (Chalcidoidea, Eulophidae)., in PLoS one
, 10, e136063.
Present-day climate warming affects the distribution of many species, making them move towards higher latitudes and altitudes as temperature rises. This project addresses the question of how much genetic variation is retained in species during range contractions. As genetic variation is the raw material for natural selection, the question of its maintenance during range contractions and contribution to the long-term evolutionary potential of species is of great importance in biology. Despite its significance, however, this question has not been studied in a multidisciplinary approach, and independent research fields have only produced a very partial vision of the processes at work. Here we build bridges among disciplines and investigate the fate of genetic diversity during range contractions using empirical datasets of an unprecedented size. Changes in species ranges are not restricted to current climate change. In fact, they have occurred many times in the past, shaping a large part of today’s biodiversity. Because modelling suggests that different speeds of contraction have dissimilar effects on genetic diversity, we will investigate processes occurring at two time scales, decadal (short term) and millennial (long term). By focusing on species that are nowadays experiencing spatial reductions of their range compared to the past, we will have direct access to processes at work during range contractions. As cold-adapted species have been particularly affected by range contractions since the last ice age they are particularly suited to such analyses.Effects of decadal range contractions will be investigated in four species of insects (one butterfly, one dragonfly, and two bumblebees) in Great Britain and Finland, two regions where the north-south orientation of land masses induces one-dimensional contraction processes. In those species, museum collections have preserved specimens captured in the last decades within and outside the current species ranges. Therefore, natural history collections offer largely underexploited direct access to the genetic diversity of the past. Effects of millennial range contractions will be examined in the silver fir, for which macrofossils (mostly needles) are available in many locations within and outside the current distribution of the species at different time points since the last glacial maximum. They will also be investigated in the Swedish cornel, for which soil samples with plant DNA residuals were obtained. Ancient DNA will be gathered from fossils, with particular care taken during extractions that will be performed in association with a specialised French laboratory.After unravelling DNA variation in modern and past specimens using next-generation-sequencing technologies, we will combine ancient and historical DNA data with spatially-explicit population and environmental niche modelling, to test hypotheses of genetic diversity loss or maintenance during range contraction. This project will therefore link state-of-the-art models with empirical examination of genetic variation, providing for the first time a direct insight into the processes responsible for the genetic patterns retrieved at contraction boundaries. Last but not least, this proposal sets the foundations for the eventual establishment of an ancient DNA laboratory in Switzerland.