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Integration of medical oncology and palliative care procedures in various institutional and economical settings: Development of tailored interventions based on patient needs and testing of its preliminary efficacy on patient reported outcomes, tumour
Applicant |
Strasser Florian
|
Number |
142226 |
Funding scheme |
Romanian-Swiss Research Programme (RSRP)
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Research institution |
Onkologische Palliativmedizin Palliativzentrum Kantonsspital St. Gallen
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Institution of higher education |
Cantonal hospital of St.Gallen - KSPSG |
Main discipline |
Clinical Cancer Research |
Start/End |
01.01.2013 - 31.12.2015 |
Approved amount |
373'320.00 |
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Keywords (1)
Chemotherapy
Lay Summary (German)
Lead
|
Integration von onkologischen und palliativmedizinischen Massnahmen in verschiedenen institutionellen und wirtschaftlichen Rahmenbedingungen: Entwicklung von massgeschneiderten, auf Patientenbedürfnissen basierenden klinischen Praxis-Instrumenten und Abschätzung ihrer möglichen Wirksamkeit für die Lebensqualität von Patienten, die Tumorkontrolle und Kosten.
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Lay summary
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Für die Betreuung von Patienten mit unheilbarer Krebskrankheit spielen Krebsspezialisten-Teams eine zentrale Rolle. Allerdings ist die Integration von palliativmedizinischen Massnahmen in die klinische Routine eine Herausforderung, insbesondere bei limitierten ökonomischen Ressourcen. Klinische Praxis- Instrumente können sowohl die Patientenbedürfnisse sichtbarer machen wie auch spezifische palliativmedizinische Massnahmen in die onkologische Praxis integrieren. Für diese Massnahmen ist eine Abschätzung ihrer Wirksamkeit auf patientenbezogene Endpunkte, Tumorkontrolle, chemotherapiebezogene Nebenwirkungen sowie Gesundheitskosten wichtig. Das gemeinschaftliche Forschungsprogramm zwischen Rumänien und der Schweiz fokussiert sich auf 5 onkologische Einrichtungen in Rumänien und eine in der Schweiz. Die Forschungshypothese ist, dass die Bereitstellung von massgeschneiderter Hilfestellung in der klinischen Praxis, basierend auf vorher erhobenen epidemiologischen Daten in jedem Institut, die Ergebnisse verbessern kann. Zuerst werden Patientendaten mit validierten Instrumenten zu Symptomen sog. palliativen Schlüsselinterventionen gesammelt. Daraufhin werden die Daten gemeinsam an einem Workshop, und unter Beizug von intl. Experten, analysiert. Anschliessend werden spezifische Interventionen (Schulungen von Krebsspezialistenteams, Einsatz von Patienten-Erfassungsinstrumenten in die Routine, Monitoring von palliativen Interventionen) in jeder der 5 Institutionen eingesetzt und ihre mögliche Wirksamkeit in einer Pilotstudie abgeschätzt. Ein abschliessender Workshop fasst die Resultate zusammen für die Weiterentwicklung in Rumänien. Unsere Arbeit hat einerseits zum Ziel, die onkologisch palliativmedizinische Versorgung in Rumänien zu optimieren. Andererseits werden die erhobenen Daten für die Planung zukünftiger Studien im Bereich der onkologischen Palliativmedizin in Ländern mit limitierten ökonomischen Ressourcen hilfreich sein.
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Responsible applicant and co-applicants
Employees
Collaboration
Institute of Oncology Bucharest |
Romania (Europe) |
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- in-depth/constructive exchanges on approaches, methods or results - Publication - Research Infrastructure |
End of Life Research Group |
Belgium (Europe) |
Institutul Oncologic Cluj |
Romania (Europe) |
|
- in-depth/constructive exchanges on approaches, methods or results - Publication - Research Infrastructure |
SAKK Statistic Group |
Switzerland (Europe) |
Regional Oncologic Institute Iasi |
Romania (Europe) |
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- in-depth/constructive exchanges on approaches, methods or results - Publication - Research Infrastructure |
Spitalul Judetean de Urgenta Alba Iulia |
Romania (Europe) |
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- in-depth/constructive exchanges on approaches, methods or results - Publication - Research Infrastructure |
Hospice Casa Sperantei |
Romania (Europe) |
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- in-depth/constructive exchanges on approaches, methods or results - Publication - Research Infrastructure |
Scientific events
Active participation
Title |
Type of contribution |
Title of article or contribution |
Date |
Place |
Persons involved |
The Conferences of the Regional Institute of Oncology Iasi, Romania (CONFER 2014)
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Talk given at a conference
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Impact of palliative care interventions on cancer outcomes
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29.11.2014
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Iasi, Romania
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Strasser Florian;
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SAKK Semi-Annual Meeting
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Talk given at a conference
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Invited presentation in the working group the network of outcome research on Mapping patient perceived need for palliative care interventions and perceived delivery of them by health care professionals.
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20.11.2014
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Bern, Switzerland
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Strasser Florian;
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ESMO Congress
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Poster
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Key Interventions of Palliative Cancer Care (KI-PCC) - patient perceived need and remembered delivery by health-care professionales (HCP): A prospective, longitudinal, multicenter study
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26.09.2014
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Madrid, Spain
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Strasser Florian;
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Oncology Days-Oncology Institute “Prof Dr I. Chiricuta"
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Poster
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Integration of medical oncology and palliative care procedures in various institutional and economical settings
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12.06.2014
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Cluj, Romania
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Achimas Patrick;
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SAKK Semi-Annual Meeting
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Talk given at a conference
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Invited presentation in the working group the ntework of outcome research on quality indicators exemplifying this project.
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20.11.2013
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Basel, Switzerland
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Strasser Florian;
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Palliative Care National Conference
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Talk given at a conference
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Early integration of oncology and palliative care on the example of cancer cachexia
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24.10.2013
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Sibiu, Romania
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Strasser Florian;
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Self-organised
3. Implementation IZERZO Project at St Luke Hospital
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16.01.2016
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Bukarest, Romania
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2. Presentation IZERZO Project Results at St Luke Hospital
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16.11.2015
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St Luke Hospital, Bucharest, Romania
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1. Presentation IZERZO Project at St Luke Hospital
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16.09.2015
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St Luke Hospital, Bucharest, Romania
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Research Seminar Palliative Care, Kantonsspital St. Gallen (Switzerland)
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28.05.2014
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Kantonsspital St Gallen, Switzerland
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Knowledge transfer events
Self-organised
Implementation of Checklists in clinical practice of medical oncologists
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20.11.2015
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Bucharest, Romania
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Communication with the public
Communication |
Title |
Media |
Place |
Year |
Talks/events/exhibitions
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Communicating the diagnosis and the prognosis- an actual problem
|
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International
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2015
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Talks/events/exhibitions
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Practical Guidelines Elaborated During the Romanian Swiss Partnership IZERZO- Integration of medica
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International
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2015
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Talks/events/exhibitions
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Research in Medical Oncology and Palliative Care
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International
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2015
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Talks/events/exhibitions
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Ïllness and Prognosis Understanding in Routine Care
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International
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2014
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Talks/events/exhibitions
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Integration of medical oncology and palliative care procedures in various institutional and economic
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International
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2014
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Talks/events/exhibitions
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Mid-term meeting
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International
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2014
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Talks/events/exhibitions
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National Congress of Romanian Society of Anaesthesia and Critical Care
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International
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2014
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Awards
Second Prize for Poster "Key Interventions of Palliative Cancer Care- Gaps between need and delivery:A longitudinal multicenter study" at Palliative Care Congress Biel (Switzerland), palliative.ch, 26th November 2014.
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2014
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Abstract
Background: In the care of advanced incurable cancer patients medical oncologists play a sentinel role in not only providing tumour directed treatment, but also in identifying and treating palliative care needs. In busy oncological clinics and more pronounced in resource restricted settings, the integration of palliative care procedures in daily practise however is challenging. Models of integrated oncology and palliative care are developing, one important is the ESMO designated centers incentive program providing 13 criteria’s. However this is linked to substantial institutional commitments, which might not be rapidly feasible on the necessary time. Therefore the provision of clinical practise tools to integrate specific palliative care procedures into daily practise of medical oncologists and testing their effects on patient reported outcomes, tumour control including anticancer treatment toxicities and also health services costs seems timely and appropriate. These interventions can be summarized under promoting of illness understanding, multidimensional symptom assessment and management, indication criteria of chemotherapy in palliative intention, care plans to promote continuity of care in support networks and proactive end of life preparation including family members. Aim: The joint research program between Romania and Switzerland focuses on 4 institutions in Romania and one institution in Switzerland. The research hypothesis is that the provision of tailored clinic practice tools, based on prior epidemiological data in each institution, can improve outcomes. Methods: The research plan includes collection of real-practice patient-based data, development of tailored educational & clinical practice tools interventions based on these results, and testing for feasibility and collection of information about preliminary efficacy on the levels patient reported outcomes, tumor control, and costs.First a workshop for protocol finalization will be conducted in Romania including the 4 institutions and the principle investigators, this to ensure development of research capacities. The second phase will include for 6 months in all 4 institutions collection of patient needs with validated tools for symptoms, but also the other for key interventions, collected by a research nurse locally spending 30 minutes per patient, who are selected randomly. Parallel the palliative outcome scale will be validated according to standard procedures and formal translation. In the third phase, data will be analyzed and a second workshop of two days conducted in Romania, including all participant research personal and selected European leaders of medical oncology in palliative care. Decisions will be made about which tailored interventions are provided in each institution. In the fourth phase these interventions will be implemented as pilot projects, mainly focusing on feasibility, led by the local institutions, supported by experts in palliative care education and in medical oncology, utilizing also the international network of educators in oncological palliative medicine (ESMO palliative care working group and international association of hospice and palliative care). Examples of interventions are the use of pain intensity, presence of depression, and weight loss (%) in every patient seen by medical oncologists. Another example includes the documentation of the goals of anticancer treatment including pre-chemotherapy evaluation of cancer-related symptoms and patient-rated importance of expected toxicities. Another example may encompass the provision of a care plan coordinating also home care services and continuity of care with the oncologist. The educational effects will be tested by knowledge tests to assure effectivity. In a fifth phase information about preliminary efficacy will be collected based on patient reported outcomes, tumour control and chemotherapy toxicities and also health services used to extrapolate costs. In the final phase this data will be also analyzed and discussed in a third workshop, where it will be decided on potential intervention trials for exploring effectiveness of new clinical practice tools and palliative care procedures webbed in medical oncology care. Expected impact: It is foreseen to publish several manuscripts based on this research, guided by investigators from Romania. The results will provide the basis for further implementation research of tailored interventions of palliative care procedures provided by medical oncologists.
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