Project

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MOMEVIP - Molecular and metabolic bases of volatile isoprenoid-induced resistance to stresses

English title MOMEVIP - Molecular and metabolic bases of volatile isoprenoid-induced resistance to stresses
Applicant Gruissem Wilhelm
Number 134415
Funding scheme Project funding (special)
Research institution Departement Umweltsystemwissenschaften ETH Zürich
Institution of higher education ETH Zurich - ETHZ
Main discipline Molecular Biology
Start/End 01.05.2011 - 30.11.2014
Approved amount 399'562.00
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All Disciplines (3)

Discipline
Molecular Biology
Ecology
Biochemistry

Keywords (7)

volatile isoprenoids; abiotic stress; apoptosis; high temperature; ozone; photosynthesis; primary metabolism

Lay Summary (English)

Lead
Lay summary

Lead

To better understand VIP functions, theMOMEVIP partners comprising six leading European laboratories and twointernational partners will develop new knowledge about the molecular andmetabolic bases of VIP biosynthesis and the functions of VIP in plantprotection.  Plant volatile isoprenoids (isoprene,monoterpenes and sesquiterpenes, collectively hereafter called VIP) playcritical roles in communication with herbivores, defense against biotic andabiotic stresses, and modulation of stress-induced signaling molecules.

Background

VIP are known to allow plants tocommunicate with other organisms, principally herbivores and their carnivoreenemies. But VIP also protect the photosynthetic apparatus against thermal andoxidative stresses. Transgenic plants that have been engineered to emitisoprene or monoterpenes, or in which isoprene biosynthesis has been repressedhave confirmed that isoprene emitters are more resistant to heat stress.Isoprene and monoterpenes reduce the damage caused by ozone and reactive oxygenspecies. In plants exposed to oxidative stresses isoprene quenches reactivenitrogen species (namely NO), which also have an important role as messengermolecules of the hypersensitive response to stress. The observation thatconstitutive VIP emission is not inhibited by stress conditions and that VIPare often induced by abiotic and biotic stresses, has therefore led to thehypothesis that a unique mechanism exists that is related to the antioxidantcapacity of VIP.

Scientific Goal

The MOMEVIP project will test currentmechanistic hypotheses on VIP functional roles using novel molecular andtechnological tools. In this way it will unravel cross-links between VIPbiosynthesis and other biochemical pathways, which may lead to changes in plantresistance to abiotic stressors and in

Significance

Improved mechanistic knowledge on VIPbiosynthesis will allow a better understanding of VIP functions, and a fullytargeted improvement of plant capacity to cope with biotic and abioticstressors, now and in the future. The results will go far beyond the scope ofMOMEVIP and will also help to improve metabolic engineering of plants for theproduction of economically interesting metabolites. Because VIP have a range ofother important functions in the interactions within the biosphere and betweenbiosphere and atmosphere, MOMEVIP advanced mechanistic knowledge will be of useto explain patterns of emission and to build predictive models of VIP emissionand reactivity in the atmosphere.

Direct link to Lay Summary Last update: 21.02.2013

Responsible applicant and co-applicants

Employees

Name Institute

Collaboration

Group / person Country
Types of collaboration
Prof. Harro Bouwmeester Netherlands (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication
- Research Infrastructure
Helmholtz Zentrum München Germany (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication
- Research Infrastructure
- Exchange of personnel
Prof. Mark Stitt, Max-Plank-Institute für Molekulare Pflanzenphysiologie Germany (Europe)
- Research Infrastructure
Prof. Han Asard Belgium (Europe)
- in-depth/constructive exchanges on approaches, methods or results
- Publication

Scientific events

Active participation

Title Type of contribution Title of article or contribution Date Place Persons involved
MOMEVIP Annual Meeting Talk given at a conference Physiological and phenotypic on Arabidopsis growth in climate change scenarios 20.03.2014 München, Germany Senning Melanie;
EUROVOL Meeting Talk given at a conference Molecular and metabolic basis of volatile isoprenoid-induced resistance to stress 04.04.2013 Florenz, Italy Senning Melanie; Gruissem Wilhelm;
MOMEVIP Annual Meeting Talk given at a conference Volatile isoprenoids improve plant stress tolerance 01.08.2012 Freiburg, Germany Senning Melanie; Gruissem Wilhelm;
MOMEVIP Annual Meeting Talk given at a conference Integrating ssoprenoid synthesis into metabolism and circadian regulation-a systems approach 05.05.2011 München, Germany Gruissem Wilhelm;


Abstract

MOMEVIP will shed new light on the biological functions of volatile isoprenoids, the most abundant plant volatiles, focusing on those traits that may help plants survive and cope with stresses exacerbated by global change. It stems from frontier research that has been carried out by all partners and that has brought fundamental advances in our knowledge of VIP functions and roles. Joining expertise in -omics and ecophysiology, and using high-throughput equipment, MOMEVIP will make possible to inspect the metabolic and molecular control of VIP biosynthesis and the subtle feedbacks that VIP induction exerts on whole plant metabolism and production.
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