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Evolutionary biology of learning in drosophila

Titel Englisch Evolutionary biology of learning in drosophila
Gesuchsteller/in Kawecki Tadeusz
Nummer 126018
Förderungsinstrument Projektförderung (Abt. I-III)
Forschungseinrichtung
Département d'Ecologie et d'Evolution Faculté de Biologie et de Médecine Université de Lausanne
Abteilung Ökologie und Evolution Departement für Biologie Universität Freiburg
Hochschule Universität Lausanne - LA
Hauptdisziplin Zoologie
Beginn/Ende 01.08.2009 - 31.07.2012
Bewilligter Betrag 537'000.00
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Keywords (11)

experimental evolution; drosophila; behaviour; behavioral genetics; learning; bonus-of-excellence; evolution; natural selection; adaptation; memory; nutritional stress

Lay Summary (Englisch)

Lead
Lay summary
The ability to learn is one of the greatest achievements of biological evolution. This project is aiming to understand how evolution may improve learning ability and memory. It uses the fruit fly Drosophila as a model system. The flies have much simpler brain and show simpler learning than mammals, but the basic neuronal mechanism of learning is the same. We previously used experimental evolution to produce 'smarter' flies, which show better learning ability and longer memory, and showed that these improved cognitive abilities come with a cost of reduced competitive ability and stress resistance. We also recently found out that moderate reduction in the amount of nutrition (caloric restriction) may improve the cognitive abilities of flies. A large part of this project will be devoted to better characterization of this phenomenon and an attempt to understand the underlying mechanism.In the long run, we hope that our research will help to understand the nature's way to improved learning and memory, and thus will contribute to better understanding of the origins of our own intelligence.We also more recently developed a project aiming at understanding how flies adapt over evolutionary time to malnutrition (poor food quality). Using experimental evolution, we bred flies with increased tolerance to malnutrition. We are currently using genomic tools and physiological assays to understand how this improved tolerance to nutritional stress was achieved, and at what cost.
Direktlink auf Lay Summary Letzte Aktualisierung: 21.02.2013

Verantw. Gesuchsteller/in und weitere Gesuchstellende

Mitarbeitende

Publikationen

Publikation
Fruit flies learn to avoid odours associated with virulent infection.
Babin Aurélie, Kolly Sylvain, Schneider Franziska, Dolivo Vassilissa, Zini Marco, Kawecki Tadeusz J (2014), Fruit flies learn to avoid odours associated with virulent infection., in Biology letters, 10(3), 20140048-20140048.
Male cognitive performance declines in the absence of sexual selection.
Hollis Brian, Kawecki Tadeusz J (2014), Male cognitive performance declines in the absence of sexual selection., in Proceedings. Biological sciences / The Royal Society, 281(1781), 20132873-20132873.
Virulent bacterial infection improves aversive learning performance in Drosophila melanogaster
Babin Aurelie, Kolly Sylvain, Kawecki Tadeusz J. (2014), Virulent bacterial infection improves aversive learning performance in Drosophila melanogaster, in Brain Behavior and Immunity, 41, 152-161.
Drosophila rely on learning while foraging under semi-natural conditions.
Zrelec Vukašin, Zini Marco, Guarino Sandra, Mermoud Julien, Oppliger Joël, Valtat Annabelle, Zeender Valérian, Kawecki Tadeusz J (2013), Drosophila rely on learning while foraging under semi-natural conditions., in Ecology and evolution, 3(12), 4139-48.
The impact of learning on selection-driven speciation.
Kawecki Tadeusz J (2013), The impact of learning on selection-driven speciation., in Trends in ecology & evolution, 28(2), 68-9.
Adaptation to Abundant Low Quality Food Improves the Ability to Compete for Limited Rich Food in Drosophila melanogaster
Vijendravarma RK, Narasimha S, Kawecki TJ (2012), Adaptation to Abundant Low Quality Food Improves the Ability to Compete for Limited Rich Food in Drosophila melanogaster, in PLOS ONE, 7(1), e30650-e30650.
Chronic malnutrition favours smaller critical size for metamorphosis initiation in Drosophila melanogaster
Vijendravarma RK, Narasimha S, Kawecki TJ (2012), Chronic malnutrition favours smaller critical size for metamorphosis initiation in Drosophila melanogaster, in JOURNAL OF EVOLUTIONARY BIOLOGY, 25(2), 288-292.
Evolution of foraging behaviour in response to chronic malnutrition in Drosophila melanogaster.
Vijendravarma Roshan K, Narasimha Sunitha, Kawecki Tadeusz J (2012), Evolution of foraging behaviour in response to chronic malnutrition in Drosophila melanogaster., in Proceedings. Biological sciences / The Royal Society, 279(1742), 3540-3546.
Experimental evolution
Kawecki TJ, Lenski RE, Ebert D, Hollis B, Olivieri I, Whitlock MC (2012), Experimental evolution, in Trends in Ecology and Evolution, 27(10), 547-560.
Adaptation to larval malnutrition does not affect fluctuating asymmetry in Drosophila melanogaster
Vijendravarma RK, Narasimha S, Kawecki TJ (2011), Adaptation to larval malnutrition does not affect fluctuating asymmetry in Drosophila melanogaster, in Biological Journal of the Linnear Society, 104, 19-28.
Plastic and evolutionary responses of cell size and number to larval malnutrition in Drosophila melanogaster
Vijendravarma RK, Narasimha S, Kawecki TJ (2011), Plastic and evolutionary responses of cell size and number to larval malnutrition in Drosophila melanogaster, in JOURNAL OF EVOLUTIONARY BIOLOGY, 24(4), 897-903.
Dietary restriction affects lifespan but not cognitive aging in Drosophila melanogaster
Burger JMS, Buechel SD, Kawecki TJ (2010), Dietary restriction affects lifespan but not cognitive aging in Drosophila melanogaster, in Aging Cell, 9(3), 327-335.
Effects of inbreeding on aversive learning in Drosophila
Nepoux V, Haag CR, Kawecki TJ (2010), Effects of inbreeding on aversive learning in Drosophila, in JOURNAL OF EVOLUTIONARY BIOLOGY, 23(11), 2333-2345.
Evolutionary ecology of learning: insights from fruit flies
Kawecki TJ (2010), Evolutionary ecology of learning: insights from fruit flies, in POPULATION ECOLOGY, 52(1), 15-25.

Zusammenarbeit

Gruppe / Person Land
Formen der Zusammenarbeit
Isabelle Olivieri, University of Montpellier Frankreich (Europa)
- Publikation
Richard Lenski / Michigan State University Vereinigte Staaten von Amerika (Nordamerika)
- Publikation
Bruno Lemaitre / EPFL Schweiz (Europa)
- vertiefter/weiterführender Austausch von Ansätzen, Methoden oder Resultaten
Michael Whitlock / University of British Columbia Kanada (Nordamerika)
- Publikation
Christoph Haag / University of Fribourg Schweiz (Europa)
- vertiefter/weiterführender Austausch von Ansätzen, Methoden oder Resultaten
- Publikation
Dieter Ebert / University of Basel Schweiz (Europa)
- Publikation

Wissenschaftliche Veranstaltungen

Aktiver Beitrag

Titel Art des Beitrags Titel des Artikels oder Beitrages Datum Ort Beteiligte Personen
Frist Joint Evolution Congress (SSE, ESEB, SSB, ASN) Vortrag im Rahmen einer Tagung Predatory cannibalism in Drosophila 06.06.2012 Ottawa, Kanada Vijendravarma Roshan;
13th Congress or the European Society for Evolutionary Biology Vortrag im Rahmen einer Tagung Experimental evolution of tolerance to chronic malnutrition in Drosophila: from life history to genomics 21.08.2011 Tubingen, Deutschland Kawecki Tadeusz; Vijendravarma Roshan;
Gordon Conference: Genes and Behavior Vortrag im Rahmen einer Tagung Adaptive and evolutionary significance of learning 14.03.2010 Vetura, California, Vereinigte Staaten von Amerika Kawecki Tadeusz;
12th Congress of the European Society for Evolutionary Biology Poster Intearction between immunity and learning 24.08.2009 Turin, Italien Babin Aurélie; Kawecki Tadeusz;


Verbundene Projekte

Nummer Titel Start Förderungsinstrument
112509 Evolutionary biology of learning in drosophila: part 2 01.08.2006 Projektförderung (Abt. I-III)
151851 Nutritional status and learning in a model species: applying honey bee techniques to Drosophila 01.12.2013 Internationale Kurzaufenthalte

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