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Interactions of silver and cerium oxide nanoparticles with the alga Chlamydomonas reinhardtii: influence of particle physico-chemical characteristics

Titel Englisch Interactions of silver and cerium oxide nanoparticles with the alga Chlamydomonas reinhardtii: influence of particle physico-chemical characteristics
Gesuchsteller/in Behra Renata
Nummer 119857
Förderungsinstrument Projektförderung (Abt. I-III)
Forschungseinrichtung Umwelttoxikologie EAWAG
Hochschule Eidg. Anstalt für Wasserversorgung, Abwasserreinigung und Gewässerschutz - EAWAG
Hauptdisziplin Andere Gebiete der Umweltwissenschaften
Beginn/Ende 01.04.2008 - 31.03.2011
Bewilligter Betrag 274'500.00
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Keywords (9)

inorganic nanoparticles; environmental fate and effects; algae; metal nanoparticles; metal dissolution; fate; toxicity; mechanisms; cell wall

Lay Summary (Englisch)

Lead
Lay summary
Engineered nanoparticles (NP) form a basis for many nanomaterials and are currently produced in a wide variety of types for a variety of applications. Their incorporation in a multitude of consumer products has recently raised questions on potential environmental consequences. Increasing production and use of materials purposefully designed for human exposure as cosmetics, food additives and textiles, or for environmental exposure as agricultural products are expected to enter the aquatic environment. Currently, only few studies have looked at how engineered nanoparticles will affect the environment and how the environment will affect nanoparticles.
The present project aims at gathering scientific information on the environmental fate and effects of silver and cerium oxide NPs. Silver NPs belong to the most important materials incorporated in consumer products and used because of their toxicity to microorganisms. Cerium oxide is industrially relevant in its use as catalyst. Specific objectives of the project are:
•to examine how physicochemical characteristics of the model NPs are influenced by factors relevant for natural waters;
•to examine sorption of the NPs to the alga C. reinhardtii;
•to examine whether NPs are toxic to algae;
•to assess which physicochemical characteristics of the NPs are determinant for sorption and toxicity.
To address these questions we will use the green algae Chlamydomonas reinhardtii as a model organism. Short-term experiments will be carried out to examine sorption and effects of NPs. Considered endpoints include photosynthesis, formation of reactive oxygen species, oxidative stress and thiol peptides involved in cellular metal homeostasis. Strong emphasis will be put on the characterization of the particles. Parameters including particle size and shape, surface area, agglomeration state, surface charge of experimental nanoparticles will also be examined under conditions of natural waters. The fundamental physical properties of the particles outlined above will be determined using a combination of different analytical techniques, such as microscopy (analytical TEM, SEM), dynamic light scattering and zeta potential measurements.
Understanding interactions between NPs and organisms requires an understanding of the chemical reactivity and aggregation behaviour of engineered NPs. Thus, the project will adopt a multisciplinary approach combining chemical, biological and particle-analysis methods.
Direktlink auf Lay Summary Letzte Aktualisierung: 21.02.2013

Verantw. Gesuchsteller/in und weitere Gesuchstellende

Mitarbeitende

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Nummer Titel Start Förderungsinstrument
128778 Confocal Microscopy at Eawag 01.09.2010 R'EQUIP
134750 Interactions of silver and cerium oxide nanoparticles with the alga Chlamydomonas reinhardtii: influence of particle physico-chemical characteristics. 01.04.2011 Projektförderung (Abt. I-III)
134750 Interactions of silver and cerium oxide nanoparticles with the alga Chlamydomonas reinhardtii: influence of particle physico-chemical characteristics. 01.04.2011 Projektförderung (Abt. I-III)
144340 Interactions cerium oxide nanoparticles with phototrophic organisms: influence of particle physico-chemical characteristics. 01.12.2012 Projektförderung (Abt. I-III)

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