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Understanding and improving malaria diagnosis in health facilities in Dar es Salaam, Tanzania

English title Understanding and improving malaria diagnosis in health facilities in Dar es Salaam, Tanzania
Applicant Lengeler Christian
Number 109696
Funding scheme Resource not found: 'bd31932a-e257-46d9-9dba-079f6f2c77c6'
Research institution Abt. öff. Gesundheitswesen und Epidemiologie Schweizerisches Tropen- und Public Health-Institut
Institution of higher education University of Basel - BS
Main discipline Tropical Medicine
Start/End 01.01.2006 - 30.06.2009
Approved amount 517'860.00
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All Disciplines (4)

Tropical Medicine
Methods of Epidemiology and Preventive Medicine
Infectious Diseases
Public Health and Health Services

Keywords (6)

malaria; fever; health services; sub-Saharan Africa; child health; clinical management

Lay Summary (English)

Lay summary
In Dar es Salaam, Tanzania, access to malaria treatment is satisfactory but a recent series of studies demonstrated that only a small fraction of all fever episodes in children and adults were actually due to malaria.This has two major consequences: firstly, there is substantial over-treatment with malaria drugs (95-99% of all treatments areunnecessary) and secondly, there is a very much increased risk of missing an alternative diagnosis with potentially fatal consequences. To address this issue of high public health importance we plan to undertake two related work components:

(1) Introducing laboratory diagnosis for malaria in the routine management of fever cases; we propose to introduce either rapid diagnostic tests based on the detection of the Plasmodium antigen (RDTs), or improve existing microscopy facilities. The focus of this operational research is to document how feasible and effective the introduction of laboratory tests is in the context of the routine management of fever cases.

(2) Understanding the aetiologies of fever cases in children; in this second work component we will be screening a sub-group of 300 children with detailed clinical assessments and a range of laboratory tests in order to better identify the diversity of the causes of fever in children aged 1-9 years.

As a result of this work we hope to be able to improve the diagnostic approach and management of fever cases in health facilities in Dar es Salaam, contribute to a more efficient and effective health sector, and help Tanzania on its way to reducing infant and child mortality.
Direct link to Lay Summary Last update: 21.02.2013

Responsible applicant and co-applicants


Associated projects

Number Title Start Funding scheme
124023 Improving quality of health care for Tanzanian children: Assessing the use of electronic decision support to promote evidence-based medicine and rational use of drugs 01.09.2009 Resource not found: 'bd31932a-e257-46d9-9dba-079f6f2c77c6'