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The Swiss National Cohort: a platform for longitudinal research in Switzerland

English title The Swiss National Cohort: a platform for longitudinal research in Switzerland
Applicant Gutzwiller Felix
Number 108806
Funding scheme Cohort Studies Large
Research institution Institut für Epidemiologie, Biostatistik und Prävention Universität Zürich
Institution of higher education University of Zurich - ZH
Main discipline Methods of Epidemiology and Preventive Medicine
Start/End 01.07.2006 - 30.06.2011
Approved amount 1'873'918.00
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All Disciplines (3)

Discipline
Methods of Epidemiology and Preventive Medicine
Sociology
Public Health and Health Services

Keywords (6)

longitudinal studies; record linkage; mortality; census; swiss health survey; completebess of follow up

Lay Summary (German)

Lead
Lay summary
1. ZieleIn der Schweiz sind keine Daten über die Entstehung von Krankheiten oder über die Erhaltung von Gesundheit vorhanden, die für die Gesamtbevölkerung repräsentativ sind. Wie sich eine Person verhielt, bevor sie krank wurde und welche Faktoren sich auf den Gesundheitszustand auswirken, lässt sich aus herkömmlichen Querschnittstudien nicht schliessen. Dazu sind so genannte longitudinale Untersuchungen nötig, die eine möglichst hohe Zahl von Personen und eine möglichst lange Untersuchungsperiode einschliessen. Mit der Swiss National Cohort soll eine landesweite Datenbasis erstellt werden, mit der Analysen über den Zusammenhang von soziodemografischen Rahmenbedingungen und individueller sozialer Lage einerseits und todesursachenspezifischer Sterblichkeit sowie gesundheitsbezogenen Variablen andererseits durchgeführt werden können. Im weiteren soll die Datenbasis zur Entwicklung von Masszahlen zum sozioökonomischen Status genutzt werden.2. Kontext und BedeutungIn der Swiss National Cohort (SNC) werden Informationen aus den Volkszählungen 1970, 1980, 1990 und 2000 mit den Sterbefällen ab 1990 zusammengeführt; für die ausländische Bevölkerung können zusätzlich Informationen über Ein- und Auswanderungen herangezogen werden. Aufgrund der so verbundenen Daten lässt sich beispielsweise herausfinden, ob es einen Zusammenhang zwischen Scheidungen und Sterbefällen gibt oder welche Verbindungen zwischen bestimmten Berufen und spezifischen Todesursachen bestehen. Damit können gesundheitliche Risiken besser beurteilt werden, und es lassen sich auch gesundheitspolitische Fragestellungen verfolgen. Weil über dasselbe Individuum häufig Angaben aus unterschiedlichen Lebensphasen verfügbar sind, können neuartige und komplexe Fragestellungen untersucht werden. Die Swiss National Cohort soll aber auch einen Mehrwert für andere Studien bilden, die damit ihre eigenen Studien mit Informationen über den sozioökonomischen Status und das soziodemografische Umfeld vervollständigen können.3. Wissenschaftlicher Rahmen und Methodologie Getragen wird das Projekt von den fünf Schweizer Instituten für Sozial- und Präventivmedizin in Zürich, Bern, Lausanne, Basel und Genf. Kernstück ist ein Kooperationsvertrag zwischen dem Bundesamt für Statistik und den Instituten in Bern und Zürich. Alle Daten stehen den Forschenden nur in anonymisierter Form zur Verfügung. Es ist also nicht bekannt, welche Namen und Adressen sich dahinter verbergen. Damit Informationen aus verschiedenen Quellen dennoch einem Individuum zugeordnet werden können, werden Variablen miteinander verglichen, die in beiden Datensätzen vorkommen, wie zum Beispiel Geschlecht, Alter und Wohnort. Stimmen diese Variablen überein, kann darauf geschlossen werden, dass es sich um die Daten desselben Individuums handelt. Bei Nicht-Übereinstimmungen wird anhand von Wahrscheinlichkeitsüberlegungen entschieden, welche Datensätze miteinander verknüpft werden können und welche nicht (sogenanntes probabilistisches Record Linkage).Linkwww.swissnationalcohort.ch
Direct link to Lay Summary Last update: 21.02.2013

Responsible applicant and co-applicants

Employees

Publications

Publication
Decreasing mortality and changing patterns of causes of death in the Swiss HIV Cohort Study.
Weber R, Ruppik M, Rickenbach M, Spoerri A, Furrer H, Battegay M, Cavassini M, Calmy A, Bernasconi E, Schmid P, Flepp M, Kowalska J, Ledergerber B, Ledergerber B (2013), Decreasing mortality and changing patterns of causes of death in the Swiss HIV Cohort Study., in HIV medicine, 14(4), 195-207.
A Swiss neighbourhood index of socioeconomic position: development and association with mortality.
Panczak Radoslaw, Galobardes Bruna, Voorpostel Marieke, Spoerri Adrian, Zwahlen Marcel, Egger Matthias, Egger Matthias (2012), A Swiss neighbourhood index of socioeconomic position: development and association with mortality., in Journal of epidemiology and community health, 66(12), 1129-36.
Body mass index vs cholesterol in cardiovascular disease risk prediction models.
Faeh David, Braun Julia, Bopp Matthias (2012), Body mass index vs cholesterol in cardiovascular disease risk prediction models., in Archives of internal medicine, 172(22), 1766-8.
Cancer, a disease of aging (part 1) - trends in older adult cancer mortality in Switzerland 1991-2008.
Schmidlin Kurt, Spoerri Adrian, Egger Matthias, Zwahlen Marcel, Stuck Andreas, Clough-Gorr Kerri M, Clough-Gorr Kerri M (2012), Cancer, a disease of aging (part 1) - trends in older adult cancer mortality in Switzerland 1991-2008., in Swiss medical weekly, 142, 13637-13637.
Cancer, a disease of aging (part 2) - risk factors for older adult cancer mortality in Switzerland 1991-2008.
Schmidlin Kurt, Spoerri Adrian, Egger Matthias, Zwahlen Marcel, Stuck Andreas, Clough-Gorr Kerri M, Clough-Gorr Kerri M (2012), Cancer, a disease of aging (part 2) - risk factors for older adult cancer mortality in Switzerland 1991-2008., in Swiss medical weekly, 142, 13607-13607.
Health risk or resource? Gradual and independent association between self-rated health and mortality persists over 30 years.
Bopp Matthias, Braun Julia, Gutzwiller Felix, Faeh David, Faeh David (2012), Health risk or resource? Gradual and independent association between self-rated health and mortality persists over 30 years., in PloS one, 7(2), 30795-30795.
Healthy migrants but unhealthy offspring? A retrospective cohort study among Italians in Switzerland.
Tarnutzer Silvan, Bopp Matthias, Bopp Matthias (2012), Healthy migrants but unhealthy offspring? A retrospective cohort study among Italians in Switzerland., in BMC public health, 12, 1104-1104.
Socioeconomic inequalities in homicide mortality: a population-based comparative study of 12 European countries.
Stickley Andrew, Leinsalu Mall, Kunst Anton E, Bopp Matthias, Strand Bjørn Heine, Martikainen Pekka, Lundberg Olle, Kovács Katalin, Artnik Barbara, Kalediene Ramune, Rychtaříková Jitka, Wojtyniak Bogdan, Mackenbach Johan P (2012), Socioeconomic inequalities in homicide mortality: a population-based comparative study of 12 European countries., in European journal of epidemiology, 27(11), 877-84.
Socioeconomic inequalities in mortality from conditions amenable to medical interventions: do they reflect inequalities in access or quality of health care?
Plug Iris, Hoffmann Rasmus, Artnik Barbara, Bopp Matthias, Borrell Carme, Costa Giuseppe, Deboosere Patrick, Esnaola Santi, Kalediene Ramune, Leinsalu Mall, Lundberg Olle, Martikainen Pekka, Regidor Enrique, Rychtarikova Jitka, Strand Björn Heine, Wojtyniak Bogdan, Mackenbach Johan P (2012), Socioeconomic inequalities in mortality from conditions amenable to medical interventions: do they reflect inequalities in access or quality of health care?, in BMC public health, 12, 346-346.
Childhood cancer and nuclear power plants in Switzerland: a census-based cohort study.
Spycher Ben, Feller Martin, Zwahlen Marcel, Röösli Martin, von der Weid Nicolas, Hengartner Heinz, Egger Matthias, Kuehni Claudia (2011), Childhood cancer and nuclear power plants in Switzerland: a census-based cohort study., in Int.J.Epidemiol. , 40, 1247-1260.
Educational inequalities in tuberculosis mortality in sixteen European populations.
Álvarez J L, Kunst A E, Leinsalu M, Bopp M, Strand B H, Menvielle G, Lundberg O, Martikainen P, Deboosere P, Kalediene R, Artnik B, Mackenbach J P, Richardus J H (2011), Educational inequalities in tuberculosis mortality in sixteen European populations., in The international journal of tuberculosis and lung disease : the official journal of the Internation, 15(11), 1461-7.
Gender differences in social mortality differentials in Switzerland (1990-2005)
Schumacher Reto, Vilpert Sarah (2011), Gender differences in social mortality differentials in Switzerland (1990-2005), in Demographic Research, 25, 285-310.
Long-term changes in social mortality differentials, Geneva, 1625-2004
Schumacher Reto, Oris Michel (2011), Long-term changes in social mortality differentials, Geneva, 1625-2004, in Explorations in Economic History, 48(3), 357-365.
Marital status, living arrangement and mortality: does the association vary by gender?
Staehelin Katharina, Schindler Christian, Spoerri Adrian, Zemp Stutz Elisabeth, Zemp Stutz Elisabeth (2011), Marital status, living arrangement and mortality: does the association vary by gender?, in Journal of epidemiology and community health, 66(7), 22-22.
Mortality from road traffic accidents in Switzerland: longitudinal and spatial analyses.
Spoerri Adrian, Egger Matthias, von Elm Erik (2011), Mortality from road traffic accidents in Switzerland: longitudinal and spatial analyses., in Accid.Anal.Prev , 43(1), 40-48.
Obesity but not overweight is associated with increased mortality risk.
Faeh David, Braun Julia, Tarnutzer Silvan, Bopp Matthias (2011), Obesity but not overweight is associated with increased mortality risk., in European journal of epidemiology, 26(8), 647-55.
Public health significance of four cardiovascular risk factors assessed 25 years ago in a low prevalence country.
Faeh David, Braun Julia, Tarnutzer Silvan, Bopp Matthias (2011), Public health significance of four cardiovascular risk factors assessed 25 years ago in a low prevalence country., in European journal of preventive cardiology, 20(1), 151-60.
Record Linkage der Todesfälle in der Statistik der Sozialmedizinischen Institutionen 2006-2008 mit der Swiss National Cohort
Zellweger Ueli, Bopp Matthias (2011), Record Linkage der Todesfälle in der Statistik der Sozialmedizinischen Institutionen 2006-2008 mit der Swiss National Cohort, Institut für Sozial- und Präventivmedizin, Zürich.
Aircraft noise, air pollution, and mortality from myocardial infarction.
Huss Anke, Spoerri Adrian, Egger Matthias, Röösli Martin (2010), Aircraft noise, air pollution, and mortality from myocardial infarction., in Epidemiology, 21(6), 829-836.
Educational inequalities in mortality and associated risk factors: German--versus French-speaking Switzerland.
Faeh David, Bopp Matthias, Bopp Matthias (2010), Educational inequalities in mortality and associated risk factors: German--versus French-speaking Switzerland., in BMC public health, 10, 567-567.
Establishing a follow-up of the Swiss MONICA participants (1984-1993): record linkage with census and mortality data.
Bopp Matthias, Braun Julia, Faeh David, Gutzwiller Felix, Gutzwiller Felix (2010), Establishing a follow-up of the Swiss MONICA participants (1984-1993): record linkage with census and mortality data., in BMC public health, 10, 562-562.
Family characteristics as risk factors for childhood acute lymphoblastic leukemia: a population-based case-control study.
Feller Martin, Adam Martin, Zwahlen Marcel, Brazzola Pierluigi, Niggli Felix, Kuehni Claudia (2010), Family characteristics as risk factors for childhood acute lymphoblastic leukemia: a population-based case-control study., in PLoS ONE, 5(10), e13156.
Religion and assisted and non-assisted suicide in Switzerland: National Cohort Study.
Spoerri Adrian, Zwahlen Marcel, Bopp Matthias, Gutzwiller Felix, Egger Matthias, Egger Matthias (2010), Religion and assisted and non-assisted suicide in Switzerland: National Cohort Study., in International journal of epidemiology, 39(6), 1486-94.
Religious Affiliation and Mortality in Switzerland, 1991-2004
Lerch Mathias, Oris Michel, Wanner Philippe, Forney YannicAs in other European countries the religious landscape of Switzerland has diversified (2010), Religious Affiliation and Mortality in Switzerland, 1991-2004, in Population, 65(2), 239-272.
Suicide in HIV-infected individuals and the general population in Switzerland, 1988-2008.
Keiser Olivia, Spoerri Adrian, Brinkhof Martin W G, Hasse Barbara, Gayet-Ageron Angéle, Tissot Frédéric, Christen Anna, Battegay Manuel, Schmid Patrick, Bernasconi Enos, Egger Matthias, Egger Matthias, Egger Matthias (2010), Suicide in HIV-infected individuals and the general population in Switzerland, 1988-2008., in The American journal of psychiatry, 167(2), 143-50.
The Swiss National Cohort: a unique database for national and international researchers.
Spoerri Adrian, Zwahlen Marcel, Egger Matthias, Bopp Matthias (2010), The Swiss National Cohort: a unique database for national and international researchers., in International journal of public health, 55(4), 239-42.
Cohort Profile: the Swiss National Cohort--a longitudinal study of 6.8 million people.
Bopp Matthias, Spoerri Adrian, Zwahlen Marcel, Gutzwiller Felix, Paccaud Fred, Braun-Fahrländer Charlotte, Rougemont André, Egger Matthias (2009), Cohort Profile: the Swiss National Cohort--a longitudinal study of 6.8 million people., in International journal of epidemiology, 38(2), 379-84.
Culture, risk factors and mortality: can Switzerland add missing pieces to the European puzzle?
Faeh D, Minder C, Gutzwiller F, Bopp M, Bopp M (2009), Culture, risk factors and mortality: can Switzerland add missing pieces to the European puzzle?, in Journal of epidemiology and community health, 63(8), 639-45.
Educational inequalities in avoidable mortality in Europe.
Stirbu Irina, Kunst Anton E, Bopp Matthias, Leinsalu Mall, Regidor Enrique, Esnaola Santiago, Costa Giuseppe, Martikainen Pekka, Borrell Carme, Deboosere Patrik, Kalediene Ramune, Rychtarikova Jitka, Artnik Barbara, Mackenbach Johan P (2009), Educational inequalities in avoidable mortality in Europe., in Journal of epidemiology and community health, 64(10), 913-20.
Lower mortality from coronary heart disease and stroke at higher altitudes in Switzerland.
Faeh David, Gutzwiller Felix, Bopp Matthias, Bopp Matthias (2009), Lower mortality from coronary heart disease and stroke at higher altitudes in Switzerland., in Circulation, 120(6), 495-501.
Residence near power lines and mortality from neurodegenerative diseases: longitudinal study of the Swiss population.
Huss Anke, Spoerri Adrian, Egger Matthias, Röösli Martin, Röösli Martin (2009), Residence near power lines and mortality from neurodegenerative diseases: longitudinal study of the Swiss population., in American journal of epidemiology, 169(2), 167-75.
Educational differences in cancer mortality among women and men: a gender pattern that differs across Europe.
Menvielle G, Kunst A E, Stirbu I, Strand B H, Borrell C, Regidor E, Leclerc A, Esnaola S, Bopp M, Lundberg O, Artnik B, Costa G, Deboosere P, Martikainen P, Mackenbach J P (2008), Educational differences in cancer mortality among women and men: a gender pattern that differs across Europe., in British journal of cancer, 98(5), 1012-9.
Socioeconomic inequalities in diabetes mellitus across Europe at the beginning of the 21st century.
Espelt A, Borrell C, Roskam A J, Rodríguez-Sanz M, Stirbu I, Dalmau-Bueno A, Regidor E, Bopp M, Martikainen P, Leinsalu M, Artnik B, Rychtarikova J, Kalediene R, Dzurova D, Mackenbach J, Kunst A E (2008), Socioeconomic inequalities in diabetes mellitus across Europe at the beginning of the 21st century., in Diabetologia, 51(11), 1971-9.
Die Swiss National Cohort 1990-2000 – eine soziodemografische Datenbasis für longitudinale Gesundheitsanalysen. Swiss National Cohort Report Nr. 5
Bopp Matthias, Gutzwiller Felix (2007), Die Swiss National Cohort 1990-2000 – eine soziodemografische Datenbasis für longitudinale Gesundheitsanalysen. Swiss National Cohort Report Nr. 5, Institut für Sozial- und Präventivmedizin der Universität Zürich, Zürich.
Socioeconomic inequalities in alcohol related cancer mortality among men: to what extent do they differ between Western European populations?
Menvielle Gwenn, Kunst Anton E, Stirbu Irina, Borrell Carme, Bopp Matthias, Regidor Enrique, Heine Strand Bjørn, Deboosere Patrick, Lundberg Olle, Leclerc Annette, Costa Giuseppe, Chastang Jean-Francois, Esnaola Santiago, Martikainen Pekka, Mackenbach Johan P (2007), Socioeconomic inequalities in alcohol related cancer mortality among men: to what extent do they differ between Western European populations?, in International journal of cancer, 121(3), 649-55.
The reversed social gradient: higher breast cancer mortality in the higher educated compared to lower educated. A comparison of 11 European populations during the 1990s.
Strand Bjørn Heine, Kunst Anton, Huisman Martijn, Menvielle Gwenn, Glickman Myer, Bopp Matthias, Borell Carme, Borgan Jens Kristian, Costa Giuseppe, Deboosere Patrick, Regidor Enrique, Valkonen Tapani, Mackenbach Johan P, Mackenbach Johan P (2007), The reversed social gradient: higher breast cancer mortality in the higher educated compared to lower educated. A comparison of 11 European populations during the 1990s., in European journal of cancer (Oxford, England : 1990), 43(7), 1200-7.

Associated projects

Number Title Start Funding scheme
134276 Swiss Cohort Study on Air Pollution and Lung and Heart Diseases in Adults (SAPALDIA) 01.04.2011 Cohort Studies Large
134273 The Swiss National Cohort: a platform for longitudinal research in Switzerland 01.07.2011 Cohort Studies Large
133139 The epidemiology of suicide assisted by right-to-die organisations in Switzerland 01.05.2011 Project funding (Div. I-III)

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