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Dissecting the formation, dynamics and interaction of coiled doils at atomic detail: Intermediate filaments, the stalk domain of a heterodimeric kinesin and the unusual leucine zipper of the Nek2 kinase

Applicant Aebi Ueli
Number 100448
Funding scheme Project funding (Div. I-III)
Research institution M.E.Müller-Institut für hoch- auflösende Elektronenmikroskopie Biozentrum
Institution of higher education University of Basel - BS
Main discipline Structural Research
Start/End 01.04.2003 - 31.03.2009
Approved amount 882'130.00
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Keywords (6)

Protein coiled coils; protein oligomerization; intermediate filaments; vimentin; keratins; nuclear lamins

Responsible applicant and co-applicants


Associated projects

Number Title Start Funding scheme
118427 Tinkering with a cellular nanomachine: A minimalist approach to studying nuclear pore complex function by de novo design 01.10.2007 Project funding (Div. I-III)
53028 Structure, formation and interaction of coiled-coils: cortexillinGCN4 and intermediate filaments 01.04.1998 Project funding (Div. I-III)